Directions: Apply small amount of serum with fingertips to freshly cleansed and toned face, neck and d�collet� areas. Avoid eye contact. Allow time to absorb prior to moisturizer application. Use Retinol serum only at night. Note: Use only as directed. If irritation persists, discontinue use & consult a physician. Prior to sun exposure, use a physical or non-toxic sunscreen. Avoid sunburn. Use of Retinol should be of limited frequency & duration. Don�t use if you are pregnant or nursing. For optimal results, use the JES Organics complete skin care regime.